The Hamburg Spitalerhof Centre is located in a corner building that fronts onto Spitalerstraße, which crosses one of the city's most popular shopping streets Kurze Mühren, with a separate wing on Lilienstrasse. Offices within the building have been arranged in an E-shape to maximise natural light, and there is a courtyard with a pond. There is parking garage for longterm tenants. The centre is situated in the central business district of Altstadt, Hamburg's old town, which runs along the southern shore of the Binnenalster lake. Streets surrounding the Hamburg Spitalerhof Centre have been recently redeveloped and local office buildings are attracting a range of new tenants. Its neighbours include architects and personnel consultants.